In a clinical trial, half of the metastatic colon or rectal cancer patients treated with LONSURF® (trifluridine and tipiracil) tablets were still alive at
7.1 months and half of the patients who received placebo were still alive at 5.3 months. Worsening of the disease
or death occurred in 88% of patients treated with LONSURF and 94% of patients who received placebo.
Taking care of you
Find ideas on maintaining balance in your life, and where you can turn for help.
Interested in receiving a LONSURF Starter Kit?
The LONSURF Starter Kit is meant to help your loved one get the most out of their treatment. The materials provided are not meant to replace a healthcare provider's advice. Always speak with a healthcare provider about any questions or concerns you or your loved one have. Together you, your loved one, and their healthcare provider can develop a personalized treatment plan based on their needs.
The LONSURF Starter Kit includes the following items:
- LONSURF Treatment Companion
Contains helpful information you and your loved one should know about mCRC and LONSURF, including how to obtain treatment and financial support and ways to help manage common side effects while taking LONSURF
- Treatment Calendar (pen included)
Provides a place to record how your loved one is feeling each day. Your loved one can take it to their appointments to help them remember what they want to discuss
- LONSURF Offerings Flashcard
Describes just a few of the helpful online resources available to you and your loved one during their treatment journey with LONSURF
- LONSURF Pillboxes
Are designed to help your loved one organize their medicine. One pillbox is for the first week of every treatment cycle (days 1 to 7), and the other is for the second week of every treatment cycle (days 8 to 14)
- Carrying Case
Can help your loved one keep their LONSURF materials in 1 place—whether they're at home, at their appointments, or anywhere else
To check your loved one's temperature regulary
LONSURF may cause serious side effects, including:
- Low blood counts. Low blood counts are common with LONSURF and can sometimes be severe and life‑threatening. LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death. Your healthcare provider should do blood tests before you receive LONSURF, at day 15 during treatment with LONSURF, and as needed to check your blood cell counts. Your healthcare provider may lower your dose of LONSURF or stop LONSURF if you have low white blood cell or platelet counts
Tell your healthcare provider right away if you get any of the following signs and symptoms of infection during treatment with LONSURF: fever, chills, or body aches.
Before taking LONSURF, tell your healthcare provider about all of your medical conditions, including if you:
- Have kidney or liver problems
Are pregnant or plan to become pregnant. LONSURF can harm your unborn baby
- Females who can become pregnant should use effective birth control during treatment with LONSURF. Tell your healthcare provider immediately if you become pregnant
- Males, while on treatment and for 3 months after your last dose of LONSURF, you should use a condom during sex with female partners who are able to become pregnant. Tell your healthcare provider right away if your partner becomes pregnant while you are taking LONSURF
- Are breast‑feeding or plan to breast‑feed. It is not known if LONSURF passes into your breast milk. Do not breast‑feed during treatment with LONSURF and for 1 day after your last dose of LONSURF
Tell your healthcare provider about all the prescription and over‑the‑counter medicines, vitamins, and herbal supplements you take.
The most common side effects with LONSURF include tiredness, nausea, decreased appetite, diarrhea, vomiting, abdominal pain, and fever.
Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away.
These are not all of the possible side effects of LONSURF. For more information, ask your healthcare provider. Call your doctor for medical advice about side effects.